Understanding Pediatric Bipolar Disorder: Why Accurate Diagnosis Matters

Today is World Bipolar Day, and we’re shining a light on a topic that’s often misunderstood: bipolar disorder in children and preteens. Early recognition is important, but misdiagnosis can have lasting consequences. Here’s what parents, caregivers, and educators need to know.

Why Diagnosis Can Be Tricky

Diagnosing bipolar disorder in children isn’t easy. Kids can naturally experience mood swings, irritability, or low energy, and these behaviors can look similar to bipolar symptoms. There isn’t a separate set of rules for diagnosing bipolar disorder in children, so providers often rely on the same criteria used for adults—making the process even more complicated.

Experts also disagree on how often true bipolar disorder appears in children. Some say mania usually starts in mid-adolescence or young adulthood, while others believe it can appear earlier as brief mood episodes lasting less than a day.

The U.S. Perspective

In the past 20 years, bipolar diagnoses in children have risen dramatically in the U.S., more than any other country.

  • Children ages 5–9: ~27 per 100,000 in the U.S. vs. <1 per 100,000 in countries like Australia, England, Germany, and New Zealand.

  • Preadolescents ages 10–14: 134 per 100,000 in the U.S. vs. <4 per 100,000 elsewhere.

Despite these numbers, the true prevalence of pediatric bipolar disorder is likely similar worldwide, suggesting that many children may be receiving a false positive diagnosis.

Why False Positives Happen

Several factors can lead to misdiagnosis:

  1. Screening tools can be misleading
    The Mood Disorders Questionnaire (MDQ) is a common screening tool but can produce false positives, sometimes reflecting anxiety instead of bipolar disorder.

  2. Parent and caregiver reports
    Clinicians often rely on parents or caregivers to report behaviors. While helpful, other adults like teachers can provide important context. Relying on only one source may contribute to errors.

  3. Insurance and “up-coding”
    Sometimes diagnoses are adjusted so treatment is covered by insurance. For example, a child with oppositional defiant disorder (ODD) might have bipolar disorder listed on their chart so therapy is covered by their health insurance—helping access care but also risking a false positive.

Common Treatments

When a child is diagnosed with bipolar disorder, treatment usually involves a combination of therapy and medication—even though, in cases of misdiagnosis, they might not actually need it.

Therapies kids may be asked to do:

  • Family-focused therapy – working with parents and siblings on coping and communication

  • Cognitive behavioral therapy (CBT) – learning to manage moods and thoughts

  • Dialectical behavioral therapy (DBT) – strategies for emotional regulation and distress tolerance

Medications kids may be prescribed:

  • Several powerful medications are approved for use in children, including risperidone, aripiprazole, quetiapine, olanzapine, asenapine, and lithium (for children 12+). These drugs can have side effects, and doctors often adjust dosages depending on whether a child is experiencing mania, depression, or is in a maintenance phase.

In some situations, kids may even be hospitalized if their symptoms are considered severe or unsafe, such as in cases of mania or suicidal thoughts.

⚠️ Why this matters: For children who have been misdiagnosed, these therapies, medications, and even hospital stays may be unnecessary—yet they are still exposed to them. Highlighting this helps emphasize the real-world impact of false positive diagnoses.

Potential Consequences of Misdiagnosis

Even when a child shows mania or hypomania, it doesn’t always mean they’ll develop bipolar disorder as an adult.

Children misdiagnosed may receive medications they don’t need, which can lead to side effects like drowsiness, dizziness, restlessness, or weight gain. One study found over 30% of children on quetiapine experienced at least one adverse reaction.

This shows that while early diagnosis is important for some, overdiagnosis carries real risks, highlighting the need for careful evaluation.

Other Conditions That Can Look Like Bipolar Disorder

Some kids diagnosed with bipolar disorder may actually have:

  • Anxiety

  • ADHD

  • ODD

  • Substance use issues

Symptoms like irritability, explosive outbursts, or mood swings can overlap, making accurate diagnosis essential.

How Clinicians Can Improve Accuracy

To avoid misdiagnosis, clinicians should look for:

  • A clear change in mood or behavior from the child’s usual personality

  • Behavior more extreme than typical development

  • Impact on daily life at home, school, or with peers

  • Sufficient duration of symptoms to meet DSM-5 criteria

This careful evaluation ensures that children get the right treatment, avoiding unnecessary medications or interventions.

Final Thoughts: Awareness is Key

World Bipolar Day reminds us that bipolar disorder is serious but complex, especially in children. Parents, caregivers, and educators should stay informed, advocate for careful assessments, and seek second opinions if needed.

Early support matters—but so does accurate diagnosis. Understanding the risks of false positives helps ensure children receive the care they truly need while avoiding unnecessary treatments and side effects.

Read the full paper here.

Previous
Previous

Understanding Bipolar Disorder in Women: Mood, Cycles, and Treatment